"Ndị eze anọ" nke covaid - 19 Mkpokọta

Ọrịa nke Fraịma nke ọhụrụ nke Crown Nke ụwa ochie ewetala nnukwu ihe na mmetụta na mmetụta ndị dị na akụ na ụba ụwa, mgbanwe ọdịnala na ndụ ọdịnala ndị niile n'ụwa. Ruo ugbu a, ọ bụ ezie na mmepe nke ntiwapụ ụwa niile gbochiri ma na-achịkwa ya. Agbanyeghị, site na mmụba nkeNgosi na - 19, ụfọdụ mba ebipụtala ụdị amụba na-agbasa ngwa ngwa. N'ime ha, ọdịiche coronavirus ọhụrụ coronavirus mere na United Kingdom, South Africa, Brazil, India, wdg.

• Alfa pụtara na England na Septemba 2020 ma kpatara ya na oge oyi, na-ewetara United Kingdoland azụ na mkpọchi na Jenụwarị. Mba ndị ọzọ nọ nso, ọkachasị na Europe. Dabere na Health Health Health, ọ ghọrọ ụdị kachasị na United States na mbido Eprel, yana nke May 25, ma ọ dịkarịa ala, mba 149 kọrọ nje a.
• Beta pụtara na South Africa na August 2020, na-eduga nlọghachi na -echi anya, ikpe 19, sauten, sauterasa, sauten. Dika nke May 25, opekata mpe, 102 obodo akọgoro ọnọdụ a.
• Achọpụtara gamma na obodo Amazon n'obodo Amazon na December 2020, na-akpata ọgba aghara, na-emebi usoro ahụike Brazil ma na-akpata ụkọ oxygen. Dị ka nke May 25, opekata mpe mba 59 akọwo ọnọdụ a.
• Achọpụtara Delta na India na Ọktọba 2020, dịka mbubreyo May, a chọtala nje ahụ dịkarịa ala, mba 54. Ndị otu egwuregwu bọọlụ na-eme ihe nkiri na-eme ihe nkiri kwuru na May 13 na ọnụego nnyefe ya nwere ike ịbụ 50% dị elu karịa nke Alfa Variant

N'afọ 2019 - NCOV bụ nke beta Genes nke Coronavirs. Ọ bụ otu - trunded dị mma - nje virus nwere ennow na envelopu. Na irighiri ihe ahụ bụ gburugburu ma ọ bụ elliptical ma nwee dayameta nke 60 - 140nm. O nwere mkpụrụ ndụ ihe dị mkpa 5, nke a na-ejikarị 4 proteị proteins nkeProtein nucleocepid (N),Protein sevelop (E),Enyombone protein (m) naSpikeGlycoproprotein (S), naHEmagglutnin - Esterasedimer (RDRP). Oseihe nwaanyiProtein nucleocepid (N) kechie rna Key na-etolite nucleococid. Nucleocpapdid na-e envelop en envelopu (e) maka nchebe. Na virus envelopu, enwereEnyombone protein (m) naSpikeGlycoproprotein (S) protein hà. N'etiti ha, coronavirus ọhụrụ ahụ ji protein a na-enye mmiri na-asọ asọ na-agbaze, wee wakporo sel ndị ahụ. Spike glycoprotein bụkwa ihe dị mkpa maka usoro ahụ ji alụso ọrịa ghara ịmata nje ma na -ewepu ha na antibodies. A na-enwekarị ụdị a na-amụba anọ nke ntopute na saịtị ụfọdụ dị mkpa nke spike Glycoprotein (s), nke na-eduga na ndị na-anabata ya na-enwe ohere ma ọ bụ na-emebi ihe. Nke a mekwara ka ndị a na-amụba anọ na-aghọ isi ihe na-ekesa.

Ihe njiri mara nke alfa na beta tetant s ka ndi a:

Ndị otu ahụ dugara site na Harvard Schoollọ Akwụkwọ Ahụike na Boston bipụtara ọtụtụ usoro nyocha na akwụkwọ ọgụgụ isi "Science Vaniant. The amino acid na-agbanwe A570d na S982A nyere aka na protein na-eme ihe iji mee ka onye na-anabata ya na-anabata ngalaba ya. N'otu oge ahụ, N501Y na-abawanye onye na-emekọrịta ihe nke ngalaba nnabata na Ace2 Rectoptor. Ndị na-eme nchọpụta na-akọwapụta na mgbanwe ndị a nwere ike ikwe ka Alfa na-ebuso ụdị Cell na-enweta ihe ndị na-anabata Ace2.

Ihe nyocha nke otu na-egosikwa na na Beta nje, ihe na-ejigidedị ya na nhazi nke G614 ma nwee otu nkwụsi ike na-akwụsi ike. N501Y, K417K na RBD anaghị akpata mgbanwe dị n'etiti k417 na Ace24 na Ace21 na ACECE21. K417N na E484K nwere ike ibute nje na-agagharị RBD - 2 EPITE CINDED na nsị. Ihe na-eso a na-eme ka a na-etinye ihe dị na NTD gbanwee nke ọma nke antigen ma belata ịdị irè nke ọgwụ mgbochi mgbochi megide NTD - 1 1 EPITE. A ga-ahọpụta ụdị beta dị iche iche n'okpuru usoro nrụgide

Ihe bụ isi nke protein mutein a:

Na nnyocha e bipụtara na akwụkwọ akụkọ Science 14, 2021, ndị otu mba na-eme nchọpụta duziri nyocha na nyocha (p.1) ọhụrụ coronavirus ọhụrụ dị na Brazil. Nsonaazụ na-egosi na Garmma (P.1) Acid acid 17 pụrụ iche acid na-agbanwe, gụnyere nke atọ na-echegbu onwe gị: N501k, na K414K. N501Y na K417T na Anlensin - igbanwe enzyme 2 (Ace2), ebe E484k dị na mpaghara LOOP na mpụga ihe mgbochi Ace2. Ọ dị mma ịmara na ụdị atọ ndị a dịkwa na mpaghara South Africa (Beta, b.1.351) nke na-enweta nlebara anya, na N501Y dị iche iche na Britain (Alfa, B.1.7). N'ihi na ha yiri ka ha na-eme mgbanwe nje dị iche iche na-eme ka ọ dịkwuo ike na mkpụrụ ndụ mmadụ, n'ọnọdụ ụfọdụ, iji nyere aka na-ebipụ nje.

Isi njirimara nke Selta Mutein:

Edemede na BEORXIV na June 17, 2021 kpebisiri ike na P681R ka na-echekwa na Delta (B.1.617) site na ọmụmụ nke Delta (B.117). Site na - nnyocha omimi, a chọtara na mmụba nke P681R na-akwalite featlin - mepere emechi protein na ngwa ngwa cell. Na iji kwalite mmụba P681 iji mee ka ikike nje ahụ bulie ikike nje na-agbagha ọgwụ mgbochi.

Dabere na ihe ndị na-epidemilogical na etí n'ime "ndị eze anọ" nkeNgosi na - 19 Mkpesa nje, enwere ike ịhụ na ntiwapụ mpaghara nke ọrịa ahụ ga-abụ ọnọdụ nkịtị na-efe efe na-efe efe. Ijere amụma nke mba ndị na-efe efe na mba ndị na-enweghị ngwụsị, ụdị dị iche iche dị iche iche dị iche iche ga-abụ ngwa agha anyị dị ike megide ọrịa na-efe efe.

(Isi iyi data: onye)